Yes. Well, it probably depends on what history data is available for those timeframes, especially in backtesting. You can try it actually, there is this "Timeframe" option available where it can be used: http://prntscr.com/3kxr21
The trailing stop block does not care of the original SL/TP values... normally. If the original SL is bigger than the one in the TS block, then that SL will be set to the value in TS. If the original SL is lower there will be no reaction until the distance between the current price and SL is big enough (trailing stop + trailing step).
Someone asked about these things before, you can read my explanations here: topic/2486
