casebefx, what have you changed in Windows? Basically fxdreema.exe wants to have full access in MT4/MT5 files and folders, because it wants to write those files there, but newest Windows versions are a little bit of weird, more restrictive and "protected". Set fxdreema.exe to run as administrator, this is the best suggestion I can give.
Also make sure that you write files in the right output directories. Because now MetaTrader can work in "normal" or portable mode, and what is normal is to have experts in some strange looking folder somewhere deep in AppData. Here is a topic I wrote about these problems before: viewtopic.php?f=2&t=2374